Effect of Tranilast Oily Gel on Carrageenin-Induced Granulation in Rats.
نویسندگان
چکیده
منابع مشابه
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Tranilast (TL), an antiallergic agent, has been clinically used in the treatment of bronchial asthma, although its clinical use has been limited by its poor solubility in water, photodegradation and systemic side effects. In this study, we prepared a gel ointment containing TL nanoparticles (TLnano gel ointment), and investigated its usefulness. In addition, we demonstrated the preventive effec...
متن کاملEffect of UV-absorbing agents on photodegradation of tranilast in oily gels.
Tranilast (TL) oily gels containing UV-absorbing agents (UV absorber) were prepared, and the effect of the agents against photodegradation of TL was investigated. When 0.1% TL oily gel without UV absorber was exposed to light, TL was photochemically decomposed to the extent of 74.1% of its initial content at the end of the first hour. Although there were differences in the preventive effect on ...
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ژورنال
عنوان ژورنال: Biological and Pharmaceutical Bulletin
سال: 2000
ISSN: 0918-6158,1347-5215
DOI: 10.1248/bpb.23.80